From simulation to reality: experimental analysis of a quantum entanglement simulation with slime molds as bioelectronic components
Our team at Biofaction, alongside Zeki Seskir and Eduardo R. Miranda, recently published a study in Frontiers in Soft Matter exploring whether slime mold (Physarum polycephalum) could serve as a biological component to simulate quantum entanglement.
The project was built on the premise that if slime mold behaves like a memristor (a resistor that “remembers” its past electrical charge), it could potentially be used to represent the complex states of quantum bits. To prove this, we looked for “pinched” hysteresis curves—the specific electrical signature that identifies a memristive device.
Ultimately, we found that slime mold doesn’t actually function as a biological memristor. Despite previous claims in the literature, our experiments showed that its natural capacitance prevents it from behaving like one, which means we cannot use it to simulate quantum entanglement.
Instead, we discovered that slime mold could be described as an replacement circuit consistof of ressitors and capacitors. While this rules out quantum applications, we believe it still has potential in bio-electronics for things like signal filters and timing circuits.
Read the full paper here.
Schmidt M, Seyfried G, Reutina U, Seskir Z and Miranda ER (2025) From simulation to reality: experimental analysis of a quantum entanglement simulation with slime molds (Physarum polycephalum) as bioelectronic components. Front. Soft Matter 5:1588404. doi: 10.3389/frsfm.2025.1588404